During isoniazid therapy, the nurse should plan to provide the patient with which supplement?

During isoniazid therapy, the nurse should plan to provide the patient with which supplement?

• A. Folic acid
• B. Liver enzymes
• C. Pancreatic enzyme
• D. Vitamin D

Answer: (B)

Isoniazid can harm the liver, so the key thing to plan for is monitoring the liver to catch any signs of hepatotoxicity early. Providing liver enzyme testing means checking the blood levels of enzymes such as AST and ALT before starting therapy and then at intervals during treatment. This helps detect drug-induced liver injury even before symptoms appear. If liver enzymes rise significantly or a patient develops symptoms like fatigue, nausea, jaundice, or dark urine, the isoniazid should be re-evaluated or stopped. Other options listed don’t address this safety need. Folic acid, pancreatic enzymes, or vitamin D aren’t related to preventing or detecting isoniazid-related liver injury. While additional measures like educating the patient about signs of liver toxicity and limiting alcohol use are important, the essential plan specific to this drug is regular monitoring of liver enzymes.

Isoniazid can harm the liver, so the key thing to plan for is monitoring the liver to catch any signs of hepatotoxicity early. Providing liver enzyme testing means checking the blood levels of enzymes such as AST and ALT before starting therapy and then at intervals during treatment. This helps detect drug-induced liver injury even before symptoms appear. If liver enzymes rise significantly or a patient develops symptoms like fatigue, nausea, jaundice, or dark urine, the isoniazid should be re-evaluated or stopped.

Other options listed don’t address this safety need. Folic acid, pancreatic enzymes, or vitamin D aren’t related to preventing or detecting isoniazid-related liver injury. While additional measures like educating the patient about signs of liver toxicity and limiting alcohol use are important, the essential plan specific to this drug is regular monitoring of liver enzymes.